Background: In middle-income countries, costs limit widespred use of left ventricular assist device (LVAD) as a strategy for end-stage heart Household Cleaning, Skincare and Beauty Products failure.We aim to describe the experience of a LVAD program in a middle-income country in a hub-and-spoke model.Methods: Patients fulfilling strict inclusion an

The Pten and Tsc1 genes both encode proteins that repress mechanistic target of rapamycin (mTOR) signaling.Disruption of either gene in the brain results in epilepsy and autism-like symptoms in humans and mouse models, therefore it is important to understand the molecular and physiological events that lead from gene disruption to disease phenotypes

In the perception of writers in Germany, free Race Pants speech is under strong pressure.A survey study, in which 526 literature writers took part, reveals innumerable aspects of hate speech, online harassment, and even physical assaults.Every second person has already experienced assaults on his or her person and is also aware of attacks on collea

Complex fenestration systems typically comprise co-planar, clear and scattering layers.As there are many ways to combine layers in fenestration systems, a common approach in building simulation is to store optical properties separate for each layer.System properties are then computed employing a fast matrix formalism, often based on a directional b

BACKGROUND: Genomics studies are being revolutionized by the next generation sequencing technologies, which have made whole genome sequencing much more accessible to the average researcher.Whole genome sequencing fuse with the new technologies is a developing art that, despite the large volumes of data that can be produced, may still fail to provid